Microwave Supported Solvent Free Reaction of EMME in the Synthesis of Pyrazolopyrimidopyrimidines

Main Article Content

D. Shah Rina
M. Shah Nirmal
C. Ramani Vivek

Abstract

Diethyl ethoxy-methylenemalonate the versatile reagent used to synthesize pyrazolopyrimidopyrimidines (3) as antimicrobial agents from the reaction between EMME and 1-substituted 3-(methylthio) 3H-pyrazolo [3,4-d]pyrimidine-4-amines (1) using Gould Jacob reaction. A comparison of conventional and microwave supported solvent-free reaction has been studied.

Keywords:
EMME, pyrazolopyrimidopyrimidines, Gould-Jacob reaction, microwave heating

Article Details

How to Cite
Shah Rina, D., Shah Nirmal, M., & Vivek, C. R. (2018). Microwave Supported Solvent Free Reaction of EMME in the Synthesis of Pyrazolopyrimidopyrimidines. Asian Journal of Applied Chemistry Research, 1(1), 1-9. https://doi.org/10.9734/ajacr/2018/v1i19602
Section
Original Research Article