Synthesis, Characterization, Swiss ADME and Antimicrobial Activity of Copper (II) Complex with 2-Sulfanilamidopyrimidine: Through DFT Spectroscopic with Profound Biological Implications
Asian Journal of Applied Chemistry Research,
Sulphadiazine and their copper metal complexes are dexterous ligands, which are condensation products of primary amines with carbonyl compounds gaining importance day by day in the present scenario. Spectral characterization and examination of the potential antimicrobial and antioxidant activity of the synthesized complex were performed. The imine Cu(II) complex is characterized by FTIR and UV/Vis spectroscopy. The Stoichiometric M:L ratio was determined by Joe and Jones method. These compounds and their copper metal complex are very important in various biological systems and their medicinal and pharmaceutical fields. Schiff foundations show beneficial natural functions such as anti-inflammatory, analgesic, antimicrobial, anticonvulsant, antitubercular, anticancer, antioxidant, anthelmintic, and antiglycation. The present review summarizes information on the diverse biological activities and also highlights the recently synthesized numerous Schiff bases and their metal complex as potential bioactive core.
- Biological activity
- swiss ADME
- Cu2 metal complexes
- bioactive core
How to Cite
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