Main Article Content
The salophen ligand and its complexes of Ni(II), Co(II), Cu(II), and Mn(II) are explored in terms of synthesis, conductivity; magnetic measurements, elemental analysis, FT-IR; electronic spectra, and antibacterial activities. The 3D molecular modeling structures of the ligand and its metal complexes are obtained by using Argus lab software. The experimental data shows that the ligand is tetradentate and bonded to the metal ion via N2O2 donor atoms. Antibacterial activity of the synthesized compounds are checked against the microbes Bacillus cereus and Escherichia coli. The metal complexes exhibit antibacterial activity higher than that of the free ligand. This works contributes to the science of Schiff base compounds, in addition to stimulating the synthesis of new ligands and its complexes for the future advancement of coordination chemistry.
Mishra A, Mishra R, Pandey MD. Synthetic, spectral, structural and antimicrobial studies of some Schiff bases 3-d metal complexes. Russian Journal of Inorganic Chemistry. 2011;56(11):1757-1764.
Gunduzalp AB, Ozbay HF. The synthesis, characterization and antibacterial activities of dinuclear Ni (II), Cu (II) and Fe (III) Schiff base complexes. Russian Journal of Inorganic Chemistry. 2012;57(2):257-260.
Alaghaz A-NM, et al. Synthesis, spectroscopic identification, thermal, potentiometric and antibacterial activity studies of 4-amino-5-mercapto-S-triazole Schiff’s base complexes. Journal of Molecular Structure. 2015;1087:60-67.
Keypour H, et al. Synthesis of two new N2O4 macroacyclic Schiff base ligands and their mononuclear complexes: Spectral, X-ray crystal structural, antibacterial and DNA cleavage activity. Polyhedron. 2015;97:75-82.
Borisova NE, Reshetova MD, Ustynyuk YA. Metal-free methods in the synthesis of macrocyclic Schiff bases. Chemical reviews. 2007;107(1):46-79.
Mohammadi K, Azad SS, Amoozegar A. New tetradentate Schiff bases of 2-amino-3, 5-dibromobenzaldehyde with aliphatic diamines and their metal complexes: Synthesis, characterization and thermal stability. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2015;146:221-227.
Dhahagani K, et al. Synthesis and spectral characterization of Schiff base complexes of Cu (II), Co (II), Zn (II) and VO (IV) containing 4-(4-aminophenyl) morpholine derivatives: Antimicrobial evaluation and anticancer studies. Spectrochimica Acta Part A : Molecular and Biomolecular Spectroscopy. 2014;117:87-94.
Isse AA, Gennaro A, Vianello E. Electrochemical carboxylation of arylmethyl chlorides catalysed by [Co (salen)][H 2 salen= N, N′-bis (salicylidene) ethane-1, 2-diamine]. Journal of the Chemical Society, Dalton Transactions. 1996;(8):1613-1618.
Nelson SG, Peelen TJ, Wan Z. Mechanistic alternatives in Lewis acid-catalyzed acyl halide. aldehyde cyclocondensations. Tetrahedron letters. 1999;40(36):6541-6543.
Yoon TP, Dong VM, MacMillan DW. Development of a new Lewis acid-catalyzed Claisen rearrangement. Journal of the American Chemical Society. 1999; 121(41):9726-9727.
Asraf MA, et al. Cobalt salophen complexes for light-driven water oxidation. Catalysis Science & Technology. 2016; 6(12):4271-4282.
Asraf MA, et al. Earth-abundant metal complexes as catalysts for water oxidation; is it homogeneous or heterogeneous? Catalysis Science & Technology. 2015; 5(11):4901-4925.
Tarafder M, et al. Coordination chemistry and bioactivity of some metal complexes containing two isomeric bidentate NS Schiff bases derived from S-benzyldithiocarbazate and the X-ray crystal structures of S-benzyl-β-N-(5-methyl- 2-furylmethylene) dithiocarbazate and bis[S-benzyl-β-N-(2-furylmethylketone) dithiocarbazato] cadmium (II). Polyhedron. 2002;21(27-28):2691-2698.
Tarafder MTH, et al. Complexes of a tridentate ONS Schiff base. Synthesis and biological properties. Transition Metal Chemistry. 2000;25(4):456-460.
Patole J, et al. Schiff base conjugates of p-aminosalicylic acid as antimycobacterial agents. Bioorganic & medicinal chemistry letters. 2006;16(6):1514-1517.
Kocyigit O, Properties and synthesis of the Cr (III)-Salen/Salophen complexes containing Triphenylamine Core. Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry. 2012;42(2): 196-204.
Afsan F, et al. Synthesis, spectral and thermal characterization of selected metal complexes containing schiff base ligands with antimicrobial activities. Asian Journal of Chemical Sciences. 2018;1-19.
Mitu L, Kriza A. Synthesis and characterization of complexes of Mn (II), Co (II), Ni (II) and Cu (II) with an aroylhydrazone ligand. Asian Journal of Chemistry. 2007;19(1):658.
Schwarzenbach G, Flaschka HA. Complexometric titrations [by] G. Schwarzenbach & Flaschka H. London: Methuen; 1969.
Parekh J, et al. Synthesis and antibacterial activity of some Schiff bases derived from 4-aminobenzoic acid. Journal of the Serbian Chemical Society. 2005;70(10): 1155.
Geary WJ, The use of conductivity measurements in organic solvents for the characterisation of coordination compounds. Coordination Chemistry Reviews. 1971;7(1):81-122.
Aranha PE, et al. Synthesis, characterization, and spectroscopic studies of tetradentate Schiff base chromium (III) complexes. Polyhedron. 2007;26(7):1373-1382.
Abd‐Elzaher MM. Spectroscopic characterization of some tetradentate Schiff bases and their complexes with nickel, copper and zinc. Journal of the Chinese Chemical Society. 2001;48(2): 153-158.
Temel H, Ilhan S. Synthesis and spectroscopic studies of novel transition metal complexes with schiff base synthesized from 1, 4-bis-(o-aminophenoxy) butane and salicyldehyde. Russian journal of Inorganic Chemistry. 2009;54(4):543-547.
Wade K. Ligand field theory and its applications, BN Figgis and MA Hitchman, Wiley–VCH, New York, 2000, xviii+ 354 pages.£ 51.95, ISBN 0.471‐31776‐4. Applied Organometallic Chemistry. 2000; 14(8):449-450.
Lever ABP. Inorganic Electronic Spectroscopy. Elsevier Publishing Company, Amsterdam, London; 1968.
Haasnoot JG, Mononuclear, oligonuclear and polynuclear metal coordination compounds with 1, 2, 4-triazole derivatives as ligands. Coordination Chemistry Reviews. 2000;200:131-185.
Alizadeh M, Farzaneh F, Ghandi M. Heterogeneous catalysis in the liquid phase oxidation of alcohols by Cu (II) complexes immobilized between silicate layers of bentonite. Journal of Molecular Catalysis A: Chemical. 2003;194(1-2):283-287.
Reinen D, Friebel C, Copper (2+) in 5-coordination: A case of a second- order Jahn-Teller effect. 2. Pentachlorocuprate (3-) and other CuIIL5 complexes: Trigonal bipyramid or square pyramid? Inorganic Chemistry. 1984;23(7):791-798.
Ruggiero CE, et al. Synthesis and structural and spectroscopic characterization of mononuclear copper nitrosyl complexes: Models for nitric oxide adducts of copper proteins and copper-exchanged zeolites. Journal of the American Chemical Society. 1993;115(24): 11285-11298.
Willett RD, Gatteschi D, Kahn O. Magneto-structural correlations in exchange coupled systems; 1985.
Jana MS, et al. Octahedral Mn (II) complex with new NNO donor Schiff base ligand: Synthesis, structure, photoluminescent behavior and computational studies. Polyhedron. 2014;81:66-73.
Thompson M, MC Zerner œ A theoretical examination of the electronic structure and spectroscopy of the photosynthetic reaction center from rhodopseudomonas viridis œ J. Am. Chem. Soc. 1991;113: 8210-8215.
Thompson MA, Glendening ED, Feller D. The nature of K+/crown ether interactions: A hybrid quantum mechanical-molecular mechanical study. The Journal of Physical Chemistry. 1994;98(41):10465-10476.
Rappé AK, et al. UFF, A full periodic table force field for molecular mechanics and molecular dynamics simulations. Journal of the American Chemical Society. 1992; 114(25):10024-10035.
Casewit C, Colwell K, Rappe A. Application of a universal force field to organic molecules. Journal of the American Chemical Society. 1992; 114(25):10035-10046.
Rappe A, Colwell K, Casewit C. Application of a universal force field to metal complexes. Inorganic Chemistry. 1993;32(16):3438-3450.
Mounika K, Pragathi A, Gyanakumari C. Synthesis characterization and biological activity of a Schiff base derived from 3-ethoxy salicylaldehyde and 2-amino benzoic acid and its transition metal complexes. Journal of Scientific Research. 2010;2(3):513-513.
Tweedy B. Plant extracts with metal ions as potential antimicrobial agents. Phytopathology. 1964;55:910-914.
Thangadurai TD, Natarajan K. Mixed ligand complexes of ruthenium (II) containing α, β-unsaturated-β-ketoaminesand their antibacterial activity. Transition Metal Chemistry. 2001;26(4-5): 500-504.
Alias M, Kassum H, Shakir C. Synthesis, physical characterization and biological evaluation of Schiff base M (II) complexes. Journal of the Association of Arab Universities for Basic and Applied Sciences. 2014;15(1):28-34.