Single-step Syznthesis of Coenzyme Q0

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Yi-Yu Yan
Yong-Fu Qiu
Tian-Li Zhang
Yu-Bei He
Shi Qi
Jian-Hua Tian
Wan-Yue Luo
Yan Zhao
Jin Wang


A new method for the preparation of 2-methyl-5,6-dimethoxy-1,4-benzoquinone (Coenzyme Q0) was developed. This improved process in one step by the oxidation of 3,4,5-trimethoxytoluene to coenzyme Q0 by simple oxidation using potassium or ammonium persulfate under transition -metal free conditions.

Coenzyme Q0, 3,4,5-trimethoxytoluene, potassium persulfate.

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How to Cite
Yan, Y.-Y., Qiu, Y.-F., Zhang, T.-L., He, Y.-B., Qi, S., Tian, J.-H., Luo, W.-Y., Zhao, Y., & Wang, J. (2019). Single-step Syznthesis of Coenzyme Q0. Asian Journal of Applied Chemistry Research, 2(3-4), 1-4.
Original Research Article